Thursday, April 21, 2011

simplified diagram of the human venous system ...Image via Wikipedia
Medical News: Vascular Cause Unlikely in Multiple Sclerosis - in Clinical Context, Multiple Sclerosis from MedPage Today
The highest prevalence was seen in the progressive forms of MS, being identified in 89.4% of patients with secondary progressive disease, which suggests that chronic cerebrospinal venous insufficiency "may be a consequence rather than a cause" of MS, Zivadinov and colleagues wrote online in Neurology.
"Several studies have reported hypoperfusion of the brain parenchyma of patients with MS advancing with disease progression, and it is possible that the venous anomalies may be secondary to reduced perfusion," they explained.
When a group of Italian researchers proposed in a series of papers that venous insufficiency was the cause of MS, tremendous controversy ensued -- at least in part because deaths occurred when surgeons attempted stenting as a treatment.
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